7240977
INHBB Monoclonal Antibody (C11), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
INHBB
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Alias
activin AB beta polypeptide; activin betaB; activin beta-B chain; INHBB; Inhibin beta B chain; inhibin beta B subunit; inhibin beta subunit B; inhibin beta-B; inhibin, beta B; Inhibin, beta-2
Gene Symbols
INHBB
Isotype
IgG1 κ
Purification Method
Protein A/G
Product Type
Antibody
Clone
C11
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P09529
Gene ID (Entrez)
3625
Immunogen
Gly293-Ala407 (Accession P09529), with N-terminal His Tag
Primary or Secondary
Primary
Content And Storage
-20°C
Gene
INHBB
Related Products
Description
- The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor
- Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity
- In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease
- Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone
- Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.