7244950

Lymphotactin Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Lymphotactin

Applications

ELISA, Western Blot

Conjugate

Biotin

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P47992

Gene ID (Entrez)

6375

Immunogen

E.coli-derived Recombinant Human Lymphotactin (XCL1)

Purification Method

Antigen affinity chromatography

Gene

Xcl1

Concentration

0.1-1.0 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

PBS with no preservative

Gene Alias

AI661682; ATAC; C motif chemokine 1; chemokine (C motif) ligand 1; cytokine SCM-1; Lptn; LTN; Lymphotactin; lymphotaxin; SCM1; SCM-1; SCM1A; SCM-1a; SCM1alpha; SCM-1alpha; SCM-1-alpha; SCM1beta; SCM-1beta; SCM-1-beta; SCYC1; single cysteine motif 1a; small inducible cytokine subfamily C, member 1 (lymphotactin); small-inducible cytokine C1; XC chemokine ligand 1; X-C motif chemokine ligand 1; XCL1

Gene Symbols

Xcl1

Primary or Secondary

Primary

Content And Storage

-20°C

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Description

  • AA Sequence of recombinant protein: GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Lymphotactin (XCL1)
  • Anti-Human Lymphotactin (XCL1)-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect hLymphotactin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Lymphotactin (500-P40) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant hLymphotactin
  • Western Blot: To detect hLymphotactin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL
  • Used in conjunction with compatible secondary reagents the detection limit for Recombinant hLymphotactin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P40BT-1MG will be provided as 2 x 500 μg Lymphotactin, otherwise known as XCL1, is a member of the C-chemokine family that uniquely acts as a chemoattractant for lymphocytes, but not monocytes or neutrophils, suggesting an important regulatory role in lymphocyte trafficking and inflammation
  • Lymphotactin, shown to signal through chemokine XC receptor 1 (XCR1), is detected at the highest level in the spleen and at low levels in the lungs, small intestine and colon, and is abundantly and selectively expressed by activated T cells, in particular CD8+ T cells, and is also produced by NK cells.