89-000-612

dual specificity phosphatase 4, Mouse, Clone: 1D12, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-612-Each-of-1 In Stock ₹ 42,898.00

89-000-612 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

dual specificity phosphatase 4

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC002671

Gene Symbols

DUSP4

Immunogen

DUSP4 (AAH02671, 1 a.a. ∼ 394 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Cell Cycle

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunofluorescence, Western Blot

Clone

1D12

Description

Mouse monoclonal antibody raised against a full length recombinant DUSP4.

Gene

DUSP4

Gene Alias

HVH2/MKP-2/MKP2/TYP

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

1846

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG3 κ

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Description

  • The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily
  • These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues
  • They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation
  • Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli
  • This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus
  • Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene
  • In addition, multiple polyadenylation sites have been reported
  • [provided by RefSeq Sequence: MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC