89-000-615

E2F transcription factor 6, Mouse, Clone: 1F7-A9, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-615-Each-of-1 In Stock ₹ 42,898.00

89-000-615 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

E2F transcription factor 6

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC008348

Gene Symbols

E2F6

Immunogen

E2F6 (AAH08348, 1 a.a. ∼ 281 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Cell Cycle

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunofluorescence, Western Blot

Clone

1F7-A9

Description

Mouse monoclonal antibody raised against a full length recombinant E2F6.

Gene

E2F6

Gene Alias

E2F-6/MGC111545

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

1876

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a κ

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Description

  • Description This gene encodes a member of the E2F transcription factor protein family
  • E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins
  • They are also a target of the transforming proteins of small DNA tumor viruses
  • Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
  • The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains
  • It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription
  • The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max
  • Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms
  • [provided by RefSeq Sequence: MSQQRPARKLPSLLLDPTEETVRRRCRDPINVEGLLPSKIRINLEDNVQYVSMRKALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKKSKNHIRWIGSDLSNFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENERLAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEVEQGQTSNKRSEGVGTSSSESTHPEGPEEEENPQQSEELLEVSN