89-000-680
GTP cyclohydrolase 1, Mouse, Clone: 2C4, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-000-680-Each-of-1 | In Stock | ₹ 42,898.00 |
89-000-680 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
GTP cyclohydrolase 1
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC025415
Gene Symbols
GCH1
Immunogen
GCH1 (AAH25415.1, 1 a.a. ∼ 250 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Whole Molecule
Yes
Gene ID (Entrez)
2643
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Applications
ELISA, Immunofluorescence
Clone
2C4
Description
Mouse monoclonal antibody raised against a full length recombinant GCH1.
Gene
GCH1
Gene Alias
DYT14/DYT5/GCH/GTP-CH-1/GTPCH1
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- This gene encodes a member of the GTP cyclohydrolase family
- The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate
- BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases
- Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia
- Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme
- [provided by RefSeq Sequence: MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRSEEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS