89-014-090
doublecortin, Mouse, Clone: 1G12, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-014-090-Each-of-1 | In Stock | ₹ 42,898.00 |
89-014-090 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
doublecortin
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC027925
Gene Symbols
DCX
Immunogen
DCX (AAH27925, 1 a.a. ∼ 360 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Research Discipline
Signal Transduction
Gene ID (Entrez)
1641
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Applications
ELISA, Immunofluorescence, Western Blot
Clone
1G12
Description
Mouse monoclonal antibody raised against a full length recombinant DCX.
Gene
DCX
Gene Alias
DBCN/DC/LISX/SCLH/XLIS
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation
- The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules
- The encoded protein contains two doublecortin domains, which bind microtubules
- In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex
- Mutations in this gene are a cause of X-linked lissencephaly
- Multiple transcript variants encoding at least three different isoforms have been found for this gene
- [provided by RefSeq Sequence: MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM