89-000-784
SMAD family member 2, Mouse, Clone: 3G9, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-000-784-Each-of-1 | In Stock | ₹ 47,882.00 |
89-000-784 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,882.00
GST (18%): ₹ 8,618.76
Total Price: ₹ 56,500.76
Antigen
SMAD family member 2
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC025699
Gene Symbols
SMAD2
Immunogen
SMAD2 (AAH25699, 181 a.a. ∼ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Whole Molecule
Yes
Gene ID (Entrez)
4087
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2b κ
Applications
ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Clone
3G9
Description
Mouse monoclonal antibody raised against a partial recombinant SMAD2.
Gene
SMAD2
Gene Alias
JV18/JV18-1/MADH2/MADR2/MGC22139/MGC34440/hMAD-2/hSMAD2
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C
- elegans gene Sma
- SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways
- This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein
- In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the same protein have been observed
- [provided by RefSeq] Sequence: PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYY