89-000-845
Notch homolog 3 (Drosophila), Mouse, Clone: 2E2, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-000-845-Each-of-1 | In Stock | ₹ 45,078.50 |
89-000-845 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,078.50
GST (18%): ₹ 8,114.13
Total Price: ₹ 53,192.63
Antigen
Notch homolog 3 (Drosophila)
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_000435
Gene Symbols
NOTCH3
Immunogen
NOTCH3 (NP_000426, 47 a.a. ∼ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Whole Molecule
Yes
Gene ID (Entrez)
4854
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Applications
ELISA, Immunofluorescence, Western Blot
Clone
2E2
Description
Mouse monoclonal antibody raised against a partial recombinant NOTCH3.
Gene
NOTCH3
Gene Alias
CADASIL/CASIL
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch
- In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development
- Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined
- Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
- [provided by RefSeq Sequence: SPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR