89-000-987

staufen, RNA binding protein, homolog 1 (Drosophila), Mouse, Clone: 1E7, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-987-Each-of-1 In Stock ₹ 42,898.00

89-000-987 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

staufen, RNA binding protein, homolog 1 (Drosophila)

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_004602

Gene Symbols

STAU1

Immunogen

STAU1 (NP_004593, 401 a.a. ∼ 496 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Whole Molecule

Yes

Gene ID (Entrez)

6780

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2b κ

Applications

ELISA, Immunofluorescence, Western Blot

Clone

1E7

Description

Mouse monoclonal antibody raised against a partial recombinant STAU1.

Gene

STAU1

Gene Alias

FLJ25010/STAU

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

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Description

  • Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles
  • These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures
  • The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin
  • The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation
  • Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described
  • Three of these variants encode the same isoform, however, differ in their 5'UTR
  • [provided by RefSeq] Sequence: PHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC