89-000-911

legumain, Mouse, Clone: M2, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-911-Each-of-1 In Stock ₹ 42,898.00

89-000-911 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

legumain

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC003061

Gene Symbols

LGMN

Immunogen

LGMN (AAH03061.1, 1 a.a. ∼ 433 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Kinases

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunoprecipitation

Clone

M2

Description

Mouse monoclonal antibody raised against a partial recombinant LGMN.

Gene

LGMN

Gene Alias

AEP/LGMN1/PRSC1

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

5641

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

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Description

  • This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds
  • This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems
  • Enzyme activation is triggered by acidic pH and appears to be autocatalytic
  • Protein expression occurs after monocytes differentiate into dendritic cells
  • A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells
  • Overexpression of this gene may be associated with the majority of solid tumor types
  • This gene has a pseudogene on chromosome 13
  • Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined
  • These two variants encode the same isoform
  • [provided by RefSeq Sequence: MVWKVAVFLSVALGIGAIPIDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVINRPNGTDVYQGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFTDHGSTGILVFPNEDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVYATTAANPRESSYACYYDEKRSTYLGDWYSVNWMEDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKTISTMKVMQFQGMKRKASSPVPLPPVTHLDLTPSPDVPLTIMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLLAASEAEVEQLLSERAPLTGHSCYPEALLHFRTHCFNWHSPTYEYALRHLYVLVNLCEKPYPLHRIKLSMDHVCLGHY