89-000-940

ret proto-oncogene, Mouse, Clone: 1C6, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-000-940-Each-of-1 In Stock ₹ 42,898.00

89-000-940 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

ret proto-oncogene

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

BC003072

Gene Symbols

RET

Immunogen

RET (AAH03072, 361 a.a. ∼ 458 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Research Discipline

Kinases

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA

Clone

1C6

Description

Mouse monoclonal antibody raised against a partial recombinant RET.

Gene

RET

Gene Alias

CDHF12/HSCR1/MEN2A/MEN2B/MTC1/PTC/RET-ELE1/RET51

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Whole Molecule

Yes

Gene ID (Entrez)

5979

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a κ

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Description

  • This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation
  • This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement
  • Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma
  • Two transcript variants encoding different isoforms have been found for this gene
  • Additional transcript variants have been described but their biological validity has not been confirmed
  • [provided by RefSeq Sequence: NLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCLADLTGDAVSGRDEARSSGLGSQKHPGS