89-001-152
G protein-coupled receptor kinase interacting ArfGAP 2, Mouse, Clone: M1, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-001-152-Each-of-1 | In Stock | ₹ 42,898.00 |
89-001-152 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
G protein-coupled receptor kinase interacting ArfGAP 2
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC001379
Gene Symbols
GIT2
Immunogen
GIT2 (AAH01379, 1 a.a. ∼ 471 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Whole Molecule
Yes
Gene ID (Entrez)
9815
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a κ
Applications
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Clone
M1
Description
Mouse monoclonal antibody raised against a full length recombinant GIT2.
Gene
GIT2
Gene Alias
CAT-2/DKFZp686G01261/KIAA0148/MGC760
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Related Products
Description
- Description This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity
- GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins
- GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking
- This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility
- This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined
- The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding
- [provided by RefSeq Sequence: MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAKKKLQSLSNHLFEELAMDMYDEVDRRETDAVWLATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQGSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKSLDSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLLGKDAN