89-016-097
AKT1, Mouse, Clone: 1D4, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-016-097-Each-of-1 | In Stock | ₹ 42,898.00 |
89-016-097 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
AKT1
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC000479
Gene Symbols
AKT1
Immunogen
AKT1 (AAH00479.1, 1 a.a. ∼ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA, Immunofluorescence, Western Blot
Clone
1D4
Description
Mouse monoclonal antibody raised against a full length recombinant AKT1.
Gene
AKT1
Gene Alias
AKT/MGC99656/PKB/PKB-ALPHA/PRKBA/RAC/RAC-ALPHA
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
207
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Related Products
Description
- The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts
- AKT1 and the related AKT2 are activated by platelet-derived growth factor
- The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1
- It was shown that the activation occurs through phosphatidylinositol 3-kinase
- In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival
- Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery
- Multiple alternatively spliced transcript variants have been found for this gene
- [provided by RefSeq Sequence: MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTLHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA