89-019-096
promyelocytic leukemia, Mouse, Clone: 1D12, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-019-096-Each-of-1 | In Stock | ₹ 44,055.00 |
89-019-096 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,055.00
GST (18%): ₹ 7,929.90
Total Price: ₹ 51,984.90
Antigen
promyelocytic leukemia
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC000080
Gene Symbols
PML
Immunogen
PML (AAH00080, 411 a.a. ∼ 510 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Research Discipline
Transcription Regulation
Gene ID (Entrez)
5371
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a κ
Applications
ELISA, Immunofluorescence, In situ PLA, Western Blot
Clone
1D12
Description
Mouse monoclonal antibody raised against a partial recombinant PML.
Gene
PML
Gene Alias
MYL/PP8675/RNF71/TRIM19
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Related Products
Description
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family
- The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region
- This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor
- Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals
- The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL)
- Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus
- Alternatively spliced transcript variants encoding different isoforms have been identified
- [provided by RefSeq] Sequence: RDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVV