89-021-253

DAF, Mouse, Clone: 1G3, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-021-253-Each-of-1 In Stock ₹ 42,898.00

89-021-253 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

DAF

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_000574

Gene Symbols

CD55

Immunogen

DAF (NP_000565, 35 a.a. ∼ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA, In situ PLA, Western Blot

Clone

1G3

Description

Mouse monoclonal antibody raised against a partial recombinant DAF.

Gene

CD55

Gene Alias

CR/CROM/DAF/TC

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1604

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • This gene encodes a protein involved in the regulation of the complement cascade
  • The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells
  • Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM)
  • Two alternatively spliced transcripts encoding different proteins have been identified
  • The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels
  • Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined
  • [provided by RefSeq Sequence: DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLRGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR