89-021-412

EIF4G2, Mouse, Clone: 3B5, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-021-412-Each-of-1 In Stock ₹ 42,898.00

89-021-412 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

EIF4G2

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_001418

Gene Symbols

EIF4G2

Immunogen

EIF4G2 (NP_001409, 811 a.a. ∼ 889 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG1 κ

Applications

ELISA, Immunohistochemistry (PFA fixed), Western Blot

Clone

3B5

Description

Mouse monoclonal antibody raised against a partial recombinant EIF4G2.

Gene

EIF4G2

Gene Alias

AAG1/DAP5/FLJ41344/NAT1/p97

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1982

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G
  • The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus
  • Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes
  • In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon
  • Alternatively spliced transcript variants encoding different isoforms of this gene have been described
  • [provided by RefSeq Sequence: SFKPVMQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQ