89-022-023

F8, Mouse, Clone: 1E8, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-022-023-Each-of-1 In Stock ₹ 43,788.00

89-022-023 - Each of 1

₹ 43,788.00

In Stock

Quantity

1

Base Price: ₹ 43,788.00

GST (18%): ₹ 7,881.84

Total Price: ₹ 51,669.84

Antigen

F8

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_000132

Gene Symbols

F8

Immunogen

F8 (NP_000123, 213 a.a. ∼ 312 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Applications

ELISA, In situ PLA

Clone

1E8

Description

Mouse monoclonal antibody raised against a partial recombinant F8.

Gene

F8

Gene Alias

AHF/DXS1253E/F8B/F8C/FVIII/HEMA

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2157

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Liquid

Related Products

Img

Abnova Corporation

89-016-326

--

Img

Abnova Corporation

89-022-308

--

Img

Abnova Corporation

89-021-065

--

Img

Abnova Corporation

89-022-021

--

Img

Abnova Corporation

89-022-075

--

Img

Abnova Corporation

89-021-384

--

Img

Abnova Corporation

89-022-085

--

Img

Abnova Corporation

89-022-062

--

Description

  • This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa
  • This gene produces two alternatively spliced transcripts
  • Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex
  • This protein undergoes multiple cleavage events
  • Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc
  • This binding domain is essential for coagulant activity
  • Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder
  • [provided by RefSeq] Sequence: KFILLFAVFDEGKSWHSETKNSLMQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITF