89-104-183

C5, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-183-Each-of-1 In Stock ₹ 31,862.00

89-104-183 - Each of 1

₹ 31,862.00

In Stock

Quantity

1

Base Price: ₹ 31,862.00

GST (18%): ₹ 5,735.16

Total Price: ₹ 37,597.16

Antigen

C5

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant C5.

Gene

C5

Gene Alias

CPAMD4/FLJ17816/FLJ17822/MGC142298

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_001735

Gene Symbols

C5

Immunogen

C5 (NP_001726, 1550 a.a. to 1661 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

727

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes
  • This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge
  • An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase
  • The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components
  • Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections
  • Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis
  • [provided by RefSeq Sequence: QTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFL