89-104-744

IL6ST, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-744-Each-of-1 In Stock ₹ 30,794.00

89-104-744 - Each of 1

₹ 30,794.00

In Stock

Quantity

1

Base Price: ₹ 30,794.00

GST (18%): ₹ 5,542.92

Total Price: ₹ 36,336.92

Antigen

IL6ST

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant IL6ST.

Gene

IL6ST

Gene Alias

CD130/CDw130/GP130/GP130-RAPS/IL6R-beta

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_002184

Gene Symbols

IL6ST

Immunogen

IL6ST (NP_002175, 23 a.a. ∽ 122 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

3572

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
  • This protein functions as a part of the cytokine receptor complex
  • The activation of this protein is dependent upon the binding of cytokines to their receptors
  • vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein
  • Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis
  • Alternatively spliced transcript variants encoding distinct isoforms have been described
  • [provided by RefSeq Sequence: ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS