POMC, Mouse, Clone: 57, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-109-512-Each-of-1 | In Stock | ₹ 68,352.00 |
89-109-512 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 68,352.00
GST (18%): ₹ 12,303.36
Total Price: ₹ 80,655.36
Antigen
POMC
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Flow Cytometry (0.5-1 ug/million cells) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (1-2 ug/mL for 30 min at RT) Immunoprecipitation (1-2 ug/500 ug protein) Western Blot (0.25-0.5 ug/mL) The optimal working dilution should be determ
Gene
POMC
Gene Symbols
POMC
Immunogen
N-terminal fragment of human POMC conjugated to KLH.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
57
Description
Mouse monoclonal antibody raised against POMC.
Formulation
In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide)
Gene Alias
ACTH/CLIP/LPH/MSH/NPP/POC
Host Species
Mouse
Purification Method
Protein A/G affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5443
Content And Storage
Store at 4°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Related Products
Description
- This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases
- There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions
- The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products
- In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation
- These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides
- Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation
- Alternatively spliced transcript variants encoding the same protein have been described
- [provided by RefSeq