89-110-436

CCND1, Mouse, Clone: CY-D1, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-436-Each-of-1 In Stock ₹ 68,797.00

89-110-436 - Each of 1

₹ 68,797.00

In Stock

Quantity

1

Base Price: ₹ 68,797.00

GST (18%): ₹ 12,383.46

Total Price: ₹ 81,180.46

Antigen

CCND1

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western Blot (4 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (8 ug/mL) Immunohistochemistry (Frozen sections) (8 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CCND1

Gene Symbols

CCND1

Immunogen

Recombinant protein corresponding to full length human CCND1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Western Blot

Clone

DCS-6

Description

Mouse monoclonal antibody raised against full length recombinant CCND1.

Formulation

Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)

Gene Alias

BCL1/D11S287E/PRAD1/U21B31

Host Species

Mouse

Purification Method

Affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

595

Content And Storage

Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a

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Description

  • The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle
  • Cyclins function as regulators of CDK kinases
  • Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event
  • This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition
  • This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb
  • Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis
  • [provided by RefSeq