89-110-591

CD59, Mouse, Clone: YUK1, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-591-Each-of-1 In Stock ₹ 1,22,731.00

89-110-591 - Each of 1

₹ 1,22,731.00

In Stock

Quantity

1

Base Price: ₹ 1,22,731.00

GST (18%): ₹ 22,091.58

Total Price: ₹ 1,44,822.58

Antigen

CD59

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Flow Cyt (5-10 ug/mL) Immunoprecipitation (5-10 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CD59

Gene Symbols

CD59

Immunogen

Native purified from human cancer cel line.

Regulatory Status

RUO

Gene ID (Entrez)

966

Form

Liquid

Applications

Flow Cytometry, Immunoprecipitation

Clone

YUK1

Description

Mouse monoclonal antibody raised against native CD59.

Formulation

In PBS (0.1% proclin, 2.0% Block Ace)

Gene Alias

16.3A5/1F5/EJ16/EJ30/EL32/FLJ38134/FLJ92039/G344/HRF-20/HRF20/MAC-IP/MACIF/MEM43/MGC2354/MIC11/MIN1/MIN2/MIN3/MIRL/MSK21/p18-20

Host Species

Mouse

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

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Description

  • Description This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction
  • This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation
  • This protein also plays a role in signal transduction pathways in the activation of T cells
  • Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction
  • Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene
  • [provided by RefSeq