89-110-936

BEST1, Mouse, Clone: E6-6, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-936-Each-of-1 In Stock ₹ 98,167.00

89-110-936 - Each of 1

₹ 98,167.00

In Stock

Quantity

1

Base Price: ₹ 98,167.00

GST (18%): ₹ 17,670.06

Total Price: ₹ 1,15,837.06

Antigen

BEST1

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Gene

BEST1

Gene Symbols

BEST1

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to human BEST1.

Regulatory Status

RUO

Gene ID (Entrez)

7439

Target Species

Human, Porcine, Primate

Form

Liquid

Applications

Immunofluorescence, Western Blot

Clone

E6-6

Description

Mouse monoclonal antibody raised against synthetic peptide of BEST1.

Formulation

In buffer containing 0.09% sodium azide

Gene Alias

ARB/BEST/BMD/TU15B/VMD2

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Test Specificity

This antibody recognizes a band at ∼68 KDa on Western Blot.

Content And Storage

Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

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Description

  • This gene encodes a member of the bestrophin gene family
  • This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains
  • Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels
  • Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue
  • Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies
  • Alternative splicing results in multiple variants encoding distinct isoforms Sequence: KDHMDPYWALENRDEAHS