89-111-040

LMNA, Mouse, Clone: JoL5, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-111-040-Each-of-1 In Stock ₹ 87,487.00

89-111-040 - Each of 1

₹ 87,487.00

In Stock

Quantity

1

Base Price: ₹ 87,487.00

GST (18%): ₹ 15,747.66

Total Price: ₹ 1,03,234.66

Antigen

LMNA

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western Blot (1:50) Immunofluorescence (1:10) The optimal working dilution should be determined by the end user.

Gene

LMNA

Gene Symbols

LMNA

Immunogen

Recombinant protein corresponding to human LMNA.

Regulatory Status

RUO

Gene ID (Entrez)

4000

Target Species

Human, Mouse

Form

Liquid

Applications

Immunofluorescence, Western Blot

Clone

JoL5

Description

Mouse monoclonal antibody raised against recombinant LMNA.

Formulation

In tissue culture supernatant (0.09% sodium azide)

Gene Alias

CDCD1/CDDC/CMD1A/CMT2B1/EMD2/FPL/FPLD/HGPS/IDC/LDP1/LFP/LGMD1B/LMN1/LMNC/PRO1

Host Species

Mouse

Quantity

2 mL

Primary or Secondary

Primary

Test Specificity

Detects an un-phosphorylated form of LMNA and the epitope is mapped to the N-terminal head domain of both proteins.

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2

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Description

  • The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane
  • The lamin family of proteins make up the matrix and are highly conserved in evolution
  • During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated
  • Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression
  • Vertebrate lamins consist of two types, A and B
  • Through alternate splicing, this gene encodes three type A lamin isoforms
  • Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome
  • [provided by RefSeq