89-110-606

FADD, Mouse, Clone: T1B, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-606-Each-of-1 In Stock ₹ 70,488.00

89-110-606 - Each of 1

₹ 70,488.00

In Stock

Quantity

1

Base Price: ₹ 70,488.00

GST (18%): ₹ 12,687.84

Total Price: ₹ 83,175.84

Antigen

FADD

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Western Blot (1-4 ug/mL) The optimal working dilution should be determined by the end user.

Gene

FADD

Gene Symbols

FADD

Immunogen

Recombinant protein corresponding to human FADD.

Regulatory Status

RUO

Gene ID (Entrez)

8772

Content And Storage

Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

Applications

Immunofluorescence, Western Blot

Clone

T1B

Description

Mouse monoclonal antibody raised against recombinant FADD.

Formulation

In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)

Gene Alias

GIG3/MGC8528/MORT1

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody detects 28 KDa protein, corresponding to the apparent molecular weight of FADD in SDS-PAGE immunoblots from samples of human and mouse origins.

Form

Liquid

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Description

  • The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals
  • Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors
  • Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade
  • Knockout studies in mice also suggest the importance of this protein in early T cell development
  • [provided by RefSeq