ABL1 (phospho Y134), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-114-199-Each-of-1 | In Stock | ₹ 57,138.00 |
89-114-199 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,138.00
GST (18%): ₹ 10,284.84
Total Price: ₹ 67,422.84
Antigen
ABL1
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1.
Formulation
In PBS (0.09% sodium azide)
Gene Accession No.
NP_005148;P00519
Gene Symbols
ABL1
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y134 of human ABL1.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Dot Blot, ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Dilution
Immunohistochemistry (1:50-100) Dot Blot (1:500) The optimal working dilution should be determined by the end user.
Gene
ABL1
Gene Alias
ABL/JTK7/bcr/abl/c-ABL/p150/v-abl
Host Species
Rabbit
Purification Method
Protein G purification
Regulatory Status
RUO
Gene ID (Entrez)
25
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Related Products
Description
- The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response
- Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene
- The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia
- The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1
- The ABL1 gene is expressed as either a 6- or 7kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11
- [provided by RefSeq