SNCA Sheep anti-Human, Rat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-114-410-Each-of-1 | In Stock | ₹ 53,133.00 |
89-114-410 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,133.00
GST (18%): ₹ 9,563.94
Total Price: ₹ 62,696.94
Antigen
SNCA
Classification
Polyclonal
Description
Sheep polyclonal antibody raised against synthetic peptide of SNCA.
Formulation
Lyophilized from PBS
Gene Alias
MGC110988/NACP/PARK1/PARK4/PD1
Host Species
Sheep
Quantity
50 μg
Primary or Secondary
Primary
Test Specificity
Immunihistochemical analysis of human and rat brain indicates a high level of specificity for this antiserum. Specificity was also confirmed by western blot.
Content And Storage
Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Applications
Immunohistochemistry (PFA fixed)
Conjugate
Unconjugated
Dilution
Immunohistochemistry (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene
SNCA
Gene Symbols
SNCA
Immunogen
A synthetic peptide (conjugated diphtheria toxoid) corresponding to amino acids 108-120 of human SNCA.
Regulatory Status
RUO
Gene ID (Entrez)
6622
Target Species
Human, Rat
Form
Lyophilized
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Description
- Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
- Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively
- SNCA may serve to integrate presynaptic signaling and membrane trafficking
- Defects in SNCA have been implicated in the pathogenesis of Parkinson disease
- SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
- Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene
- [provided by RefSeq] Sequence: PQEGILEDMPVDPC