89-115-713

BCL2L1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-115-713-Each-of-1 In Stock ₹ 68,797.00

89-115-713 - Each of 1

₹ 68,797.00

In Stock

Quantity

1

Base Price: ₹ 68,797.00

GST (18%): ₹ 12,383.46

Total Price: ₹ 81,180.46

Antigen

BCL2L1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of BCL2L1.

Formulation

Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4(5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)

Gene Alias

BCL-XL/S/BCL2L/BCLX/Bcl-X/DKFZp781P2092/bcl-xL/bcl-xS

Host Species

Rabbit

Purification Method

Affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

598

Target Species

Human, Mouse, Rat

Form

Lyophilized

Applications

Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

BCL2L1

Gene Symbols

BCL2L1

Immunogen

A synthetic peptide corresponding to amino acids at internal region of human BCL2L1.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Different to the related rat sequence by a single amino acid.

Content And Storage

Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • The protein encoded by this gene belongs to the BCL-2 protein family
  • BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities
  • The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening
  • VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis
  • Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported
  • The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator
  • [provided by RefSeq