89-115-862

ALOX5 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-115-862-Each-of-1 In Stock ₹ 1,09,381.00

89-115-862 - Each of 1

₹ 1,09,381.00

In Stock

Quantity

1

Base Price: ₹ 1,09,381.00

GST (18%): ₹ 19,688.58

Total Price: ₹ 1,29,069.58

Antigen

ALOX5

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of ALOX5.

Formulation

In PBS (30% glycerol, 0.09% sodium azide)

Gene Accession No.

P09917

Gene Symbols

ALOX5

Immunogen

A synthetic peptide corresponding to amino acids 100-200 of human ALOX5.

Regulatory Status

RUO

Gene ID (Entrez)

240

Content And Storage

Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

Applications

Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.

Gene

ALOX5

Gene Alias

5-LO/5-LOX/5LPG/LOG5/MGC163204

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

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Description

  • This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid
  • The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4)
  • Leukotrienes are important mediators of a number of inflammatory and allergic conditions
  • Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers
  • Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined
  • [provided by RefSeq