89-118-575

APP Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-118-575-Each-of-1 In Stock ₹ 76,718.00

89-118-575 - Each of 1

₹ 76,718.00

In Stock

Quantity

1

Base Price: ₹ 76,718.00

GST (18%): ₹ 13,809.24

Total Price: ₹ 90,527.24

Antigen

APP

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of APP.

Formulation

In PBS (0.02% sodium azide)

Gene Accession No.

P05067

Gene Symbols

APP

Immunogen

A synthetic peptide corresponding to N-terminus 18 amino acids of human APP.

Regulatory Status

RUO

Gene ID (Entrez)

351

Content And Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene

APP

Gene Alias

AAA/ABETA/ABPP/AD1/APPI/CTFgamma/CVAP/PN2

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • Description This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides
  • Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease
  • Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy)
  • Multiple transcript variants encoding several different isoforms have been found for this gene
  • [provided by RefSeq