89-118-642

AGTR2 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-118-642-Each-of-1 In Stock ₹ 76,718.00

89-118-642 - Each of 1

₹ 76,718.00

In Stock

Quantity

1

Base Price: ₹ 76,718.00

GST (18%): ₹ 13,809.24

Total Price: ₹ 90,527.24

Antigen

AGTR2

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of AGTR2.

Formulation

In PBS (0.02% sodium azide)

Gene Accession No.

AAS45437

Gene Symbols

AGTR2

Immunogen

A synthetic peptide corresponding to internal region 16 amino acids of human AGTR2.

Regulatory Status

RUO

Gene ID (Entrez)

186

Content And Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

AGTR2

Gene Alias

AT2/ATGR2/MRX88

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion
  • It is an important effector controlling blood pressure and volume in the cardiovascular system
  • It acts through at least two types of receptors termed AT1 and AT2
  • AGTR2 belongs to a family 1 of G-protein coupled receptors
  • It is an integral membrane protein
  • It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system
  • This receptor mediates programmed cell death (apoptosis)
  • In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube
  • It is highly expressed in fetal kidney and intestine
  • The human AGTR2 gene is composed of three exons and spans at least 5kb
  • Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame
  • [provided by RefSeq]