ACVR2B, Rabbit, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-121-726-Each-of-1 | In Stock | ₹ 53,133.00 |
89-121-726 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,133.00
GST (18%): ₹ 9,563.94
Total Price: ₹ 62,696.94
Antigen
ACVR2B
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against synthetic peptide of ACVR2B.
Formulation
In PBS (0.09% sodium azide)
Gene Accession No.
NP_001097;Q13705
Gene Symbols
ACVR2B
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human ACVR2B.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Dilution
Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Gene
ACVR2B
Gene Alias
ACTRIIB/ActR-IIB/MGC116908
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
93
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
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Description
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins
- Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors
- These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
- Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors
- Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
- Type II receptors are considered to be constitutively active kinases
- This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor
- [provided by RefSeq