APOE Rabbit anti-Human, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-130-770-Each-of-1 | In Stock | ₹ 53,133.00 |
89-130-770 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,133.00
GST (18%): ₹ 9,563.94
Total Price: ₹ 62,696.94
Antigen
APOE
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against synthetic peptide of APOE.
Formulation
In PBS (0.09% sodium azide)
Gene Accession No.
NP_000032;P02649
Gene Symbols
APOE
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human APOE.
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Dilution
Western Blot (1:1000) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
Gene
APOE
Gene Alias
AD2/LPG/MGC1571/apoprotein
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
348
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
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Description
- Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver
- Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells
- ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents
- The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2
- Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants
- [provided by RefSeq