89-123-134

SNCA, Mouse, Clone: 2E4, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-123-134-Each-of-1 In Stock ₹ 43,254.00

89-123-134 - Each of 1

₹ 43,254.00

In Stock

Quantity

1

Base Price: ₹ 43,254.00

GST (18%): ₹ 7,785.72

Total Price: ₹ 51,039.72

Antigen

SNCA

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_000345

Gene Symbols

SNCA

Immunogen

SNCA (NP_000336, 31 a.a. ∼ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

Applications

ELISA, Immunoprecipitation, Western Blot

Clone

2E4

Description

Mouse monoclonal antibody raised against a partial recombinant SNCA.

Gene

SNCA

Gene Alias

MGC110988/NACP/PARK1/PARK4/PD1

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6622

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
  • Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively
  • SNCA may serve to integrate presynaptic signaling and membrane trafficking
  • Defects in SNCA have been implicated in the pathogenesis of Parkinson disease
  • SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
  • Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene
  • [provided by RefSeq] Sequence: GKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA