89-132-563

LCP2, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-132-563-Each-of-1 In Stock ₹ 70,399.00

89-132-563 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

LCP2

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:32000) Western Blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.

Gene

LCP2

Gene Symbols

LCP2

Immunogen

A synthetic peptide corresponding to human LCP2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of LCP2.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Alias

SLP-76/SLP76

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

3937

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat
  • The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice
  • The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains
  • The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation
  • SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain
  • A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein
  • Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function
  • [provided by RefSeq Sequence: ALRNVPFRSEV-C