89-133-073

UCP2, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-133-073-Each-of-1 In Stock ₹ 70,399.00

89-133-073 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

UCP2

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:4000) Western Blot (0.2-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

UCP2

Gene Symbols

UCP2

Immunogen

A synthetic peptide corresponding to internal region of human UCP2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of UCP2.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Alias

BMIQ4/SLC25A8/UCPH

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

7351

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP)
  • UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak
  • UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane
  • They also reduce the mitochondrial membrane potential in mammalian cells
  • Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known
  • UCPs contain the three homologous protein domains of MACPs
  • This gene is expressed in many tissues, with the greatest expression in skeletal muscle
  • It is thought to play a role in nonshivering thermogenesis, obesity and diabetes
  • Chromosomal order is 5'-UCP3-UCP2-3'
  • [provided by RefSeq] Sequence: C-DSVKQFYTKGSEH