COMT Goat anti-Human, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-132-631-Each-of-1 | In Stock | ₹ 70,399.00 |
89-132-631 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
COMT
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:4000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
Gene
COMT
Gene Symbols
COMT
Immunogen
A synthetic peptide corresponding to human COMT.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is expected to recognize both reported isoforms (NP_000745.1 and NP_009294.1).
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of COMT.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Accession No.
NP_000745.1;NP_009294.1
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
1312
Target Species
Human
Form
Liquid
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Description
- Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine
- This O-methylation results in one of the major degradative pathways of the catecholamine transmitters
- In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease
- COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT)
- The differences between S-COMT and MB-COMT reside within the N-termini
- Several transcript variants are formed through the use of alternative translation initiation sites and promoters
- [provided by RefSeq Sequence: GDTKEQRILNHVLQC