89-133-009

CNTFR, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-133-009-Each-of-1 In Stock ₹ 70,399.00

89-133-009 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

CNTFR

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:16000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CNTFR

Gene Alias

MGC1774

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

1271

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of CNTFR.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Accession No.

NP_671693.1;NP_001833.1

Gene Symbols

CNTFR

Immunogen

A synthetic peptide corresponding to human CNTFR.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody is expected to recognize both reported isoforms (NP_671693.1, NP_001833.1).

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors
  • The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130
  • The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain
  • Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex
  • Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types
  • Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified
  • [provided by RefSeq Sequence: CRSNTYPKGFY