89-132-661
WAS, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-132-661-Each-of-1 | In Stock | ₹ 70,399.00 |
89-132-661 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
WAS
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:128000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
Gene
WAS
Gene Symbols
WAS
Immunogen
A synthetic peptide corresponding to human WAS.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is expected to no cross-reactivity with N WASP (WASL).
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of WAS.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Alias
IMD2/THC/WASP
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
7454
Target Species
Human
Form
Liquid
Related Products
Description
- The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton
- The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins
- Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3
- Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene
- The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients
- A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known
- [provided by RefSeq] Sequence: C-SPADKKRSGKKKI