89-133-016
GALR2, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-133-016-Each-of-1 | In Stock | ₹ 70,399.00 |
89-133-016 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
GALR2
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:4000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene
GALR2
Gene Alias
GALNR2/MGC125983/MGC125984
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
8811
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of GALR2.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Accession No.
NP_0.03848.1
Gene Symbols
GALR2
Immunogen
A synthetic peptide corresponding to human GALR2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
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Description
- Description Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis
- It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility
- The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors
- GALR2 interacts with the N-terminal residues of the galanin peptide
- The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi
- However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways
- [provided by RefSeq Sequence: C-RYPLHSRELRTPRN