NCF4, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-133-138-Each-of-1 | In Stock | ₹ 70,399.00 |
89-133-138 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
NCF4
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:32000) Western blot (0.3-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) The optimal working dilution should be determined by the end user.
Gene
NCF4
Gene Symbols
NCF4
Immunogen
A synthetic peptide corresponding to human NCF4.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is expected to recognize both reported isoforms (NP_000622.2 and NP_0.38202.1).
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of NCF4.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Alias
MGC3810/NCF/P40PHOX/SH3PXD4
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
4689
Target Species
Human
Form
Liquid
Related Products
Description
- The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense
- This protein is preferentially expressed in cells of myeloid lineage
- It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation
- This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system
- The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events
- The phosphorylation of this protein was found to negatively regulate the enzyme activity
- Alternatively spliced transcript variants encoding distinct isoforms have been observed
- [provided by RefSeq Sequence: C-KDFPEEDDPTN