MBD2, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-133-005-Each-of-1 | In Stock | ₹ 70,399.00 |
89-133-005 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
MBD2
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:64000) Western blot (0.3-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) The optimal working dilution should be determined by the end user.
Gene
MBD2
Gene Symbols
MBD2
Immunogen
A synthetic peptide corresponding to internal region of human MBD2.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is expected to recognize isoform 1 (NP_0.03918.1) only.
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of MBD2.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Alias
DKFZp586O0821/DMTase/NY-CO-41
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
8932
Target Species
Human
Form
Liquid
Related Products
Description
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
- Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD)
- Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA
- MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters
- The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal
- It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing
- [provided by RefSeq Sequence: C-RNDPLNQNKGKPDLN