WISP1, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-133-222-Each-of-1 | In Stock | ₹ 70,399.00 |
89-133-222 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
WISP1
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:128000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
Gene
WISP1
Gene Symbols
WISP1
Immunogen
A synthetic peptide corresponding to human WISP1.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is expected to recognize both reported isoforms (NP_003873.1; NP_543028.1).
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of WISP1.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Alias
CCN4/WISP1c/WISP1i/WISP1tc
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
8840
Target Species
Human
Form
Liquid
Related Products
Description
- This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family
- WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes
- The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain
- This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation
- It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors
- The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation
- It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase
- It is 83% identical to the mouse protein at the amino acid level
- Alternative splicing of this gene generates 2 transcript variants
- [provided by RefSeq Sequence: C-ESYPDFSEIAN