89-333-165

CASP3 Mouse anti-Human, Clone:3D4D7, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-333-165-Each-of-1 In Stock ₹ 60,787.00

89-333-165 - Each of 1

₹ 60,787.00

In Stock

Quantity

1

Base Price: ₹ 60,787.00

GST (18%): ₹ 10,941.66

Total Price: ₹ 71,728.66

Antigen

CASP3

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

ELISA (1:10000)Western Blot (1:500-1:2000)ImmunohistochemistryImmunocytochemistryFlow Cytometry (1:200-1:400)The optimal working dilution should be determined by the end user.

Gene

CASP3

Host Species

Mouse

Quantity

100 μg

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry

Clone

3D4D7

Description

caspase 3, apoptosis-related cysteine peptidase

Formulation

In PBS (0.05% sodium azide)

Gene Alias

CPP32, CPP32B, SCA-1

Immunogen

Recombinant protein corresponding to amino acid 29-175 of human CASP3 fromE. coli.

Gene ID (Entrez)

836

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family
  • Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
  • Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme
  • This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10
  • It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer′s disease
  • Alternative splicing of this gene results in two transcript variants that encode the same protein
  • [provided by RefSeq]