89-933-735

CCR5 Mouse anti-Human, Clone: T21/8, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-933-735-Each-of-1 In Stock ₹ 85,173.00

89-933-735 - Each of 1

₹ 85,173.00

In Stock

Quantity

1

Base Price: ₹ 85,173.00

GST (18%): ₹ 15,331.14

Total Price: ₹ 1,00,504.14

Antigen

CCR5

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

ELISA Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.

Gene Alias

CC-CKR-5/CCCKR5/CD195/CKR-5/CKR5/CMKBR5/IDDM22

Host Species

Mouse

Purification Method

Affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

1234

Content And Storage

Store at 4°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1 κ

Applications

ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone

T21/8

Description

Mouse monoclonal antibody raised against human CCR5.

Formulation

In aqueous buffer (Stabilizer, 0.09% sodium azide).

Gene Symbols

CCR5

Immunogen

Human CCR5

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors
  • This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells
  • Defective alleles of this gene have been associated with the HIV infection resistance
  • The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES)
  • Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation
  • This gene is located at the chemokine receptor gene cluster region
  • Two transcript variants encoding the same protein have been found for this gene
  • [provided by RefSeq]