89-934-127
FCER1A Mouse anti-Human, Clone: AER-37 (CRA1), Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-934-127-Each-of-1 | In Stock | ₹ 85,173.00 |
89-934-127 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 85,173.00
GST (18%): ₹ 15,331.14
Total Price: ₹ 1,00,504.14
Antigen
FCER1A
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias
FCE1A/FcERI
Host Species
Mouse
Purification Method
Affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
2205
Content And Storage
Store at 4°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2b κ
Applications
Flow Cytometry, Immunohistochemistry (PFA fixed)
Clone
AER-37 (CRA1)
Description
Mouse monoclonal antibody raised against human FCER1A.
Formulation
In PBS, 150mM NaCl, pH 7.2 (0.09% sodium azide).
Gene Symbols
FCER1A
Immunogen
Human FCER1A
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
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Description
- The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma
- The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule
- A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response
- The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM]