CDKN1A Mouse anti-Human, Clone: HJ21, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-933-927-Each-of-1 | In Stock | ₹ 67,017.00 |
89-933-927 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,017.00
GST (18%): ₹ 12,063.06
Total Price: ₹ 79,080.06
Antigen
CDKN1A
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Flow Cytometry (0.5-1 ug/106cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene Alias
CAP20/CDKN1/CIP1/MDA-6/P21/SDI1/WAF1/p21CIP1
Host Species
Mouse
Purification Method
Protein A/G purification
Regulatory Status
RUO
Gene ID (Entrez)
1026
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Clone
HJ21
Description
Mouse monoclonal antibody raised against full length recombinant human CDKN1A.
Formulation
In 10mM PBS.
Gene Symbols
CDKN1A
Immunogen
Recombinant protein corresponding to full length human CDKN1A.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody is highly specific to CDKN1A and shows no cross-reaction with other closely related mitotic inhibitors.
Content And Storage
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Related Products
Description
- This gene encodes a potent cyclin-dependent kinase inhibitor
- The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1
- The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli
- This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair
- This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation
- Two alternatively spliced variants, which encode an identical protein, have been reported
- [provided by RefSeq]