89-934-239

HEXA Mouse anti-Human, Clone: AT20F1, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-934-239-Each-of-1 In Stock ₹ 85,173.00

89-934-239 - Each of 1

₹ 85,173.00

In Stock

Quantity

1

Base Price: ₹ 85,173.00

GST (18%): ₹ 15,331.14

Total Price: ₹ 1,00,504.14

Antigen

HEXA

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:3000) The optimal working dilution should be determined by the end user.

Gene Alias

MGC99608/TSD

Host Species

Mouse

Purification Method

Protein A purification

Regulatory Status

RUO

Gene ID (Entrez)

3073

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG2a λ

Applications

ELISA, Immunohistochemistry (PFA fixed), Western Blot

Clone

AT20F1

Description

Mouse monoclonal antibody raised against partial recombinant human HEXA.

Formulation

In PBS, pH 7.4 (10% glycerol, 0.02% sodium azide)

Gene Symbols

HEXA

Immunogen

Recombinant protein corresponding to amino acids 89-529 of human HEXA.

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines
  • Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes
  • Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases
  • Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses
  • Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I)
  • [provided by RefSeq]