89-934-112

ESR1 Mouse anti-Human, Clone: , Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-934-112-Each-of-1 In Stock ₹ 85,173.00

89-934-112 - Each of 1

₹ 85,173.00

In Stock

Quantity

1

Base Price: ₹ 85,173.00

GST (18%): ₹ 15,331.14

Total Price: ₹ 1,00,504.14

Antigen

ESR1

Classification

Monoclonal

Description

Mouse monoclonal antibody raised against human ESR1.

Formulation

In PBS, pH 7.4 (0.03% sodium azide).

Gene Symbols

ESR1

Immunogen

Recombinant protein corresponding to amino acids 410-592 of human ESR1.

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:800) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.

Gene Alias

DKFZp686N23123/ER/ESR/ESRA/Era/NR3A1

Host Species

Mouse

Purification Method

Protein A purification

Regulatory Status

RUO

Gene ID (Entrez)

2099

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

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Description

  • This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription
  • The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2
  • Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone
  • Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis
  • Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters
  • [provided by RefSeq]