ABE1425MI
MilliporeSigma™ anti-COUP-TF1, Polyclonal
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1425MI-Each-of-1 | In Stock | ₹ 37,706.63 |
ABE1425MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,706.63
GST (18%): ₹ 6,787.193
Total Price: ₹ 44,493.823
Antigen
COUP-TF1
Classification
Polyclonal
Formulation
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols
Nr2f1, Erbal3, Tfcoup1
Immunogen
GST-tagged recombinant protein corresponding to the N-terminal half of mouse COUP-TF1.
Quantity
100 μL
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_034281
Target Species
Human, Mouse, Rat
Form
Serum
Applications
ChIP Assay, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Gene Accession No.
Q60632
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Specificity of the antiserum was confirmed by immunogen blocking in immunohistochemistry on frozen sections (Tripodi, M., et al. (2004). Development. 131(24):6119-6129).
Content And Storage
−20°C for one year
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Description
- Specifically detects COUP-TF1 Clone: in Human, Mouse, Rat samples, and it is validated for Chromatin Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Western Blotting COUP transcription factor 1 (UniProt Q60632; also known as Avian erythroblastic leukemia viral oncogene homolog-like 3, COUP-TF1, COUP-TF I, COUP transcription factor I, EAR-3, Nuclear receptor subfamily 2 group F member 1, V-erbA-related protein 3) is encoded by the Nr2f1 (also known as Erbal3, Tfcoup1) gene (Gene ID 13865) in murine species
- COUP transcription factors1&2 (COUP-TFI, COUP-TFII) are two related nuclear orphan receptors implicated in their roles in guiding migrating neurons towards their target regions during brain development
- COUP-TFI and COUP-TFII are expressed in distinct and non-overlapping migrating cells in specific pathways in the basal telencephalon of mouse embryos at a stage when interneuron migration is robust
- While COUP-TFI appears to control dorsal and ventral migration in the basal telencephalon, COUP-TFII is more specific in modulating tangential migration into the intermediate zone of the cortex
- Coup-TFII is also identified as an activator of Prox1 expression in venous lymphatic endothelial cell (LEC) progenitors during early stages of LEC specification and differentiation.